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The healing properties of the thermal waters that flow from the Campi Flegrei have been known since ancient times, but many of the numerous spas in the area have fallen into ruin and been abandoned over the centuries due to both neglect and natural phenomena. For several years, the research group of Hydrological Chemistry of the University of Naples "Federico II" has been interested in studying the quality of the Phlegraean waters and the aim of this work was to analyze the spring "Fonte Angelica" belonging to the Cantarello group to evaluate the chemical and therapeutic characteristics. A clinical study was conducted on patients suffering from chronic rhinitis comparing the effects of mineral water with pharmacologically active substances and placebo, using qualitative assessments of subjective and objective symptoms at time zero, during treatment and at the end of the therapeutic cycle, and in parallel instrumental assessments using rhinofibroscopy and nasal cytology. In contemporary medicine, thermalism seems to be revived thanks to a renewed scientific interest aimed at re-evaluating thermal therapy as a non-invasive treatment method, simultaneously allowing us to rediscover that psychophysical well-being that is so difficult to achieve in chaotic modern life.